Tricuspid Regurgitation After TAVR Linked to Increases in Mortality, Readmission

Adult Cardiac: Aortic Valve


3:30 p.m. – 5:30 p.m.

Room 330AB

Mild or greater tricuspid regurgitation (TR) was found in more than 80% of transcatheter aortic valve replacement patients, according to a study based on data collected from the STS/American College of Cardiology TVT Registry.


Fenton H. McCarthy, MD

“Increasing degrees of TR are associated with worse survival and higher rates of readmission, and severe TR is independently associated with decreased survival in patients with preserved left ventricular ejection fraction,” said lead author Fenton H. McCarthy, MD, of Penn Medicine at the University of Pennsylvania in Philadelphia.

The study is the largest examination of the prevalence and impact of TR on patients who have received replacement aortic valves. It focused on 1-year mortality, heart failure readmission, in-hospital major adverse cardiac events (MACE), and stays in the intensive care unit and the hospital. The results of the study will be among six abstracts and a debate presented in a Tuesday session.

“The most surprising and important findings of this study are that even moderate TR was associated with increased mortality and readmission at 30 days, 6 months, and 1 year,” Dr. Fenton said. “The findings may help patients and the heart team decide on an approach to treating severe symptomatic aortic stenosis in patients with concomitant tricuspid regurgitation.”

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